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Randomised controlled trial demonstrates that fermented infant formula with short‐chain galacto‐oligosaccharides and long‐chain fructo‐oligosaccharides reduces the incidence of infantile colic

Title: Randomised controlled trial demonstrates that fermented infant formula with short‐chain galacto‐oligosaccharides and long‐chain fructo‐oligosaccharides reduces the incidence of infantile colic

Authors: Vandenplas Y, Ludwig T, Bouritius H, Alliet P, Forde D, Peeters S, Huet F, Hourihane J
Published: 2017
Journal:

Acta Paediatrica

The study examined the effects on gastrointestinal tolerance of a novel infant formula that combined a specific fermented formula with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides (scGOS/lcFOS).

The combination of scGOS/lcFOS and 50% fermented formula was particularly well tolerated, with 60% less infantile colic at four weeks of age and lower daily crying duration, and a stool softening effect in healthy term infants.

These findings suggest for the first time that a specific infant formula has a preventive effect on infantile colic in formula-fed infants.

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Citation: Vandenplas Y, Ludwig T, Bouritius H, Alliet P, Forde D, Peeters S, Huet F, Hourihane J. Randomised controlled trial demonstrates that fermented infant formula with short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides reduces the incidence of infantile colic. Acta Paediatr 2017; 106: 1150–1158